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Cache Valley virus
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Cache Valley virus : ウィキペディア英語版
Cache Valley virus

Cache Valley virus (CVV) is a member of the Bunyaviridae family, Orthobunyavirus genus, and Bunyamwera serogroup, which was first isolated in 1956 from ''Culiseta inornata'' mosquitos collected in Utah’s Cache Valley.〔Grimstad, P. (2001). Cache Valley virus. Encyclopedia of Arthropod-transmitted Infections of Man and Domesticated Animals: 101-104.〕 CVV is an enveloped arbovirus, nominally 80–120 nm in diameter, whose genome is composed of three single-stranded, negative-sense RNA segments.〔〔Sims, R., Dr. (2009, December 30). Can Cache Valley virus trash your manufacturing? (log post ). http://rmcpharmanews.blogspot.com/2009/12/can-cache-valley-virus-trash-your.html.〕 The large segment of related bunyaviruses is approximately 6800 bases in length and encodes a probable viral polymerase.〔 The middle CVV segment has a 4463-nucleotide sequence and the smallest segment encodes for the nucleocapsid, and a second non-structural protein.〔 CVV has been known to cause outbreaks of spontaneous abortion and congenital malformations in ruminants such as sheep and cattle. CVV rarely infects humans, but when they are infected it has caused encephalitis and multiorgan failure.〔Cache Valley virus. (2012). http://medical-dictionary.thefreedictionary.com/Cache Valley virus.〕
==Virology==


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